Products / Antibiotic / BEST-N

BEST-N

Generic Name: Erythromycin, Neomycin, Sulfadimidine, Trimethoprim & Bromhexine HCl Therapeutic Category : Antibiotic

10 x 100 gm & 1 x 500 gm.

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BEST-N
Composition

Each gm BEST-N (vet) powder contains- Erythromycin Estolate BP 35.98 mg, Neomycin Sulphate BP 51.73 mg, Sulfadimidine BP 100 mg, Trimethoprim BP 18 mg & Bromhexine HCl BP 1.64 mg.

Mode of action

Erythromycin is a macrolide antibiotic binding with the 50S ribosomal subunit of bacteria. Neomycin is an aminoglycoside antibiotic irreversibly binding to the 30S ribosomal subunit of bacteria. Thereby inhibits bacterial protein synthesis. Sulphadimidine inhibits nucleic acid synthesis by blocking the conversion of Para aminobenzoic Acid (PABA) to co-enzyme dihydrofolic acid & Trimethoprim inhibits bacterial nucleic acid synthesis. Bromhexine breakdown the structure of Mucopolysaccharide fiber in mucoid sputum & produces less viscous mucus, facilitates the removal of mucus by ciliary action.

Indications

BEST-N (vet) powder is active against the following conditions:

Mycoplasmosis Infectious Coryza
Coli-septicemia Pullorum Disease
Enteritis Fowl Typhoid
Bronchopneumonia Fowl Cholera
CRD CCRD

 

Dosage Administration

Route of administration: For oral administration only.
For prevention: 1 g/Liter drinking water for 4-6 days. 
For treatment: 2 g/Liter drinking water for 4-6 days. 
Or as directed by the registered Veterinarian.

Side Effects

Common side effects: Diarrhea, Anorexia, Vomiting, Crystal Urea, Anemia, Thrombocytopenia & Leukopenia, Allergic reactions, Ototoxicity, Nephrotoxicity & Intestinal Malabsorption. 
Rare side effects: Not Known.

Precautions

Use carefully in poultry with impaired liver and kidney functions. Do not use in rabbits, guinea pigs & hamsters.

Contraindications

Contraindicated in poultry hypersensitive to Erythromycin, Neomycin, Sulfadimidine, Trimethoprim & Bromhexine. 

Pregnancy Lactation

Not applicable.

Withdrawal Period

Meat- 5 days & Egg- 3 days.

Drug Interaction

With medicine: This combination reduces the absorption of oral penicillin & Vitamin K. This combination should not be used with Chloramphenicol, Lincomycin, Clindamycin & 
antifungal drugs. 
With feed & others: Not Known. 

Storage

To be dispensed & sold only by the prescription of a registered Veterinarian & should not be used more than the mentioned amount in the prescription.Fulfill the course of antibiotics according to the advice of the registered Veterinarian.

Store below 30ºC temperature & dry place, protected from light.
Keep all medicines out of reach of children.

Pack Size

10 x 100 gm & 1 x 500 gm.

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