Products / Quinolone Antibiotic / Cipryl (Vet) Bolus

Cipryl (Vet) Bolus

Generic Name: Ciprofloxacin USP Therapeutic Category : Quinolone Antibiotic

Each box contains 5 x 4’s bolus in Alu-PVC/PVDC blister.

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Cipryl (Vet) Bolus
Composition

Each bolus contains Ciprofloxacin Hydrochloride USP equivalent to Ciprofloxacin 1000 mg.

Mode of action

Ciprofloxacin is a Nalidixic acid derivative. It is synthetic  fluoroquinolone of the second generation quinolones with a broad range activity against all of the main pathogenic mycoplasma and bacteria (both gram-positive and gram-negative) affecting poultry. Ciprofloxacin blocks the functions of DNA gyrase which is essential for synthesis of DNA nucleic acid. The details on the spectrum of activity indicates that the minimum inhibitory concentration (MIC) of organism is very low for this quinolone.

 

Indications

Cipryl (Vet) is effective against several infections as Respiratory Tract infections, Gastro Intestinal infections, Enterotoxaemia, Skin, Bone & Ear infections, Uterine infections, Urinary Tract Infection, Anthrax, Dysentery etc.

 

Dosage Administration

Route of administration: For oral administration only.
Dairy: 1 bolus/75-150 kg body weight for 3-5 days.
Poultry: 1 bolus/15-20 liters water for 3-5 days.
Or as directed by the registered Veterinarian.

Side Effects

Common side effects: Central nervous system (CNS) toxicity; gastrointestinal reactions; hepatotoxicity; hypersensitivity reactions; Stevens-Johnson Syndrome (blistering, itching, peeling or redness of skin; diarrhea).
Rare side effects: Not Known.

 

Precautions

Animal receiving Ciprofloxacin should be well hydrated and should be instructed to drink fluids liberally. Because of the risk of crystalluria, it is recommended that the usual dosage of the drug should not be exceeded.

Contraindications

Animal/poultry hypersensitive to Ciprofloxacin are contra-indicated.

 

 

Pregnancy Lactation

Intravenous doses of Ciprofloxacin of up to 20 mg/kg of body weight (mg/kg) in pregnant rats and mice have not shown evidence of maternal toxicity, embryo toxicity or teratogenic effects. Ciprofloxacin can be distributed into milk, sometimes at a higher concentration than in plasma, but it is not known under what conditions significant amounts might be absorbed by nursing animals.

 

Withdrawal Period

Dairy: Meat- 14 days & Milk- 3 days.
Poultry: Meat- 6 days & Egg- Not known.

Drug Interaction

With medicine: Ciprofloxacin administered together with theophylline can lead to elevated blood levels of theophylline. Ciprofloxacin can enhance the action of the anticoagulant warfarin and increase the risk of bleeding.
With feed & others: Not Known. 

Storage

To be dispensed & sold only by the prescription of a registered Veterinarian & should not be used more than the mentioned amount in the prescription. Fulfill the course of antibiotics according to the advice of the registered Veterinarian.

Store below 30ºC temperature & dry place, protected from light.
Keep all medicines out of reach of children.

Pack Size

Each box contains 5 x 4’s bolus in Alu-PVC/PVDC blister.

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